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Acknowledgements PC3 cell lines were kindly provided by Dr C Pettaway, MD Anderson Medical Center

Tackling human fungal infections

Mitochondria produce large amounts of ROS through the oxidation-reduction reactions carried out in the respiratory chain.2 Evidence indicates that under physiological conditions, ROS may participate in redox signalling, but excessive ROS production may cause oxidative damage to proteins, lipids and DNA, and affect cellular functionality.3 Several studies indicate the role of oxidative stress in the progression of autoimmune thyroid diseases, such as Graves disease.4 ROS are neutralised by the antioxidant enzymes SOD, CAT, and GPx

PMID 9501533

24 April 2019)

There are no published clinical trial data evaluating this pairing, and it does not exist as a named investigational product or registered trial programme