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Future research should prioritize large-scale, prospective randomized controlled trials to confirm the effects of specific diets on hearing protection

Due to its high solubility, amphipathic structure, and low molecular weight, melatonin displays a high intracellular and extracellular diffusion capacity, being able to cross cell membranes and the blood-brain barrier [6,15]

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Intl J Biomed Pharma Sci
McIntyre and co-workers investigated the protective effect of BMS-345541, an IKK inhibitor, and found that it could suppress the IL-1 level to attenuate inflammation and joint destruction, contributing to alleviate collagen-induced arthritis in the mouse model [117]