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Diabetes 65 , 18001807 (2016)

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Cognitive and behavioral assessments were conducted to evaluate learning, memory, and anxiety-like behavior, including the Morris water maze, open-field test, and elevated plus maze

d , e , Xkr8 expression in BMNs from Xkr8 fl/fl and Xkr8 fl/fl Ly6G Cre mice using RT-PCR and qPCR ( n = 3), with 18S as the internal reference

Severe nausea requiring treatment discontinuation was rare in monotherapy trials, with only about 1% of participants in the REDEFINE 1 trial stopping treatment because of adverse events overall

Such metabolic reprogramming engages in complex crosstalk with inflammatory signaling pathways
