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[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Bird C.M., Burgess N

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Furthermore, our in vivo studies suggest that TRPML1 has functions in late endosome-to-lysosome transport that are earlier than those inferred from some of the terminal lysosomal defects described in cell culture models of MLIV

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Its cyclic structure, including a lactam bridge, increases stability and affinity compared to natural peptides