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Rao J, Wan X, Tou F, He Q, Xiong A, Chen X, et al

R Soc Open Sci (2018) 5(11):112

Yao B, Lu X, Xu L, Jiang Y

Cancer-associated fibroblasts promote doxorubicin resistance in triple-negative breast cancer through enhancing ZFP64 histone lactylation to regulate ferroptosis

As a result, the accumulation and dysregulation of these proteins can lead to proteotoxic stress and ultimately cell death (105, 106)

The peptide appears to work by normalizing sleep architecture rather than acutely sedating, which explains the variable onset
