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labial melanotic macule vs melanoma macules in atopic dermatitis. (a) Multiple macular Labial melanotic macule (brown spot
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b , Salinazid and fat-2 depletion act in the same pathway to extend lifespan

Animal models confirm TMAOs pathogenic role: reducing plasma TMAO slows CKD progression (138), while TMAO accelerates diabetic nephropathy by activating NLRP3 inflammasome, promoting IL-1/IL-18 release, and worsening renal dysfunction/fibrosis (139)

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Is non-HDL-cholesterol a better predictor of long-term outcome in patients after acute myocardial infarction compared to LDL-cholesterol