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Individuals randomised to placebo therapy who are not in remission after the 8 week study period will be eligible to receive 8 weeks of open label (unblinded) active FMT therapy

As illustrated in Figure 1, genetically determined increased levels of TLR2 (rs1816702) and MD-2 ( LY96 ) (rs11465996) (required for TLR2 and TLR4 to respond to LPS) 15, 16 were associated with beneficial response among patients with CD, indicating that a higher activity of TLR2 was associated with a beneficial response among patients with CD

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doi: 10.1371/journal.pone.0106335 7 SecherTKassemSBenamarMBernardIBouryMBarreauFet al