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This correlates well with the suggestion that carnitine is involved in the inflammatory response and that the expression of OCTN2 in epithelia can be modulated by inflammatory cytokines such as INF- and TNF- (Pochini et al., 2019)

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L-carnitine also has a secondary function of helping remove some waste products from the cells to prevent them from accumulating and causing health problems

Based on the evidence that heat-shock proteins (Hsps) can exert neuroprotective effects against oxidative stress-related injury and that nutritional antioxidants are able to upregulate Hsps in neurons, use of nutritional antioxidants such as carnitine/acetyl-L-carnitine has been advocated to counteract the oxidative stress-induced brain damage in Alzheimer's disease [67, 119]

Following its formation, TMA is absorbed into the bloodstream through the intestinal epithelium and transported to the liver