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The optimal protocol is to inject first thing in the morning, after an overnight fast of at least 8 hours

Eur J Pharm Sci

Geeta Sidhu-Robb, founder of Nosh Detox, which sells B12 injections and infusions at Harvey Nichols in Knightsbridge, London, believes her customers do benefit

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Advertisement Article continues below this ad Allergic Reactions Although rare, an allergic reaction may occur following a vitamin B12 injection

But controlled human efficacy data is sparse, and the single Phase 2 trial tested oral administration rather than the subcutaneous injection most users employ today