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Regulation of VWF (Von Willebrand Factor) in inflammatory thrombosis

Beyond its metabolic functions, FAD and FMN substantially influence neuroinflammatory signaling, particularly through modulation of pathways such as TNFR1/NF-B, MAPK, and PI3K-Akt

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Such multi-layered convergence aligns with previous GWAS in rice, emphasising the importance of integrating QTL, haplotype, and expression data to identify robust loci for Fe toxicity tolerance 10,32,61,92