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Immune mechanisms linking sleep deprivation and diseases As shown above, sleep deprivation has been found to alter inflammatory immune processes via multiple pathways, which could lead to increased susceptibility to chronic inflammatory diseases (Fig

A reduced proportion of CD16 + and granzyme B + NK cells and higher frequency of TIM3 + and HLADR + exhaustedNK cells was present at baseline in patients resistant to daratumumab treatment

Freile, H.J
