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doi: 10.1056/NEJMoa2111904 182 JenksJ

Conclusion: Our study provides a comprehensive metaproteomic analysis of bile samples related to gallstone disease, offering new insights into the microbiome-host interaction and gallstone formation mechanism

4.4 Regulating the gut microbiota and nervous system ENS can act as a local neural mechanism to independently control intestinal behavior and interact with the immune and endocrine systems

Amino Acids are the building blocks for collagen, which helps promote healthy skin and joints

Data availability and material Raw data are available upon request

6.3 Mechanistic understanding and complex interactions Although substantial progress has been found in recognizing the core pathways by which exercise may exert therapeutic effectsnamely through the regulation of oxidative stress and HPA axis functionour insight of the complicated relationship between these mechanisms continues to be incomplete