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In some extreme cases, there has been evidence of tingling sensation and even chest pains in those lacking B12

B12 for Pain in Peripheral Neuropathy B12 injections have been used in pain therapy for decades 1

Stomach acid and enzymes free vitamin B 12 from food, allowing it to bind to R-protein (formerly known as transcobalamin I and now called haptocorrin), found in saliva and gastric fluids
When evaluating HCG sources, consider purity, potency verification, storage and handling during shipping, and reputation

Important caveats Large-scale, long-term human outcome data are limited
