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The disorder is caused by a germline mutation in the RET gene, which encodes a receptor tyrosine kinase involved in cellular growth and differentiation
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Barakat, A
278 XieT.GengJ.WangY.WangL.HuangM.ChenJ.et al (2017)
Additionally, in patients with triple-negative breast cancer, the expression levels of SLC7A11 and ATF4 are much higher than those in normal breast tissue
Moreover, NF-B pathway activation impaired the GSH/GPX4 axis by triggering HIF-2 generation (Zhang et al., 2024c)
