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Deep wrinkles require longer consistent use and may benefit from combination with other modalities

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The only difference was observed in transdermal rivastigmine that was associated with a MCID of greater than 1.40 MMSE points against placebo in the aggregate data NMA compared with the IPD NMA, yet a statistically significant improvement was achieved in the IPD NMA

10.1016/j.trac.2023.116922 16 BaiJ.ZhangZ.LiuM.LiC
