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Therefore, the upregulation of these genes by p53 possibly serves to sensitise cells to apoptosis by cytotoxic T cells and natural killer (NK) cells, which can express the ligands for death receptors

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Amylin has been demonstrated to influence the hedonic pathway, for example, by reducing the activity of neural circuits that mediate the rewarding aspects of food consumption, although it primarily affects energy metabolism by increasing satiety (67)

doi: 10.3389/fnut.2022.947118

Peptides therapy aims to replace whatever is lost
