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There have been no documented cases of toxicity related to expired glutathione supplements

PLoS One 6 (7), e22639 (2011) R
In addition, given the cross-talk between microglia and astrocytes, this system could potentially activate A2 reactive astrocytes, which may help limit the excessive production of pro-inflammatory factors and oxidative stress molecules, ultimately restoring neural homeostasis

See also the graphical abstract(Fig