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In accordance to available medical knowledge, obesity appears to be a major environmental factor contributing to the onset and progression of autoimmune diseases [127]
doi: 10.7326/0003-4819-151-4-200908180-00135
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Surprisingly, the interactions between hypocretin neurons and their general and immune environments are presumably genotype-dependent, and thus the iPSC approach can help to elucidate it
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PMID 18661558
