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43 Serum homocysteine is less specific for B 12 deficiency, and can also be elevated in folate deficiency, vitamin B 6 deficiency, vitamin B 2 deficiency, and impaired renal function, hypothyroidism, and by certain medications

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The study concluded that progression-free survival (PFS) was 43.2% in the vaccine plus chemotherapy group compared to 35.1% in the chemotherapy-only group, although this difference was not statistically significant

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