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doi: 10.1371/journal.pone.0130997 126 GerspachACSteinertRESchnenbergerLGraber-MaierABeglingerC

Therapy of nontuberculous mycobacterial infections

3.2.3 Effects on natural killer cells Acute HIIT rapidly mobilizes natural killer (NK) cells into the peripheral blood, particularly cytotoxic subpopulations expressing CD57, CD158a, NKG2D, TIM-3, and CXCR3 (cNK), which return to baseline levels after one hour, thereby balancing the distribution of NK cell subsets (54)

Fecal excretion of total carnitine was less than 1% of the administered dose.10 After attainment of steady state following 4 days of oral administration of levocarnitine tablets (1980 mg every 12 hours) or oral solution (2000 mg every 12 hours) to 15 healthy male volunteers, the mean urinary excretion of levocarnitine during a single dosing interval (12 hours) was about 9% of the orally administered dose (uncorrected for endogenous urinary excretion)

The accumulation of ROS damages cochlear cells, particularly OHCs, leading to apoptosis and subsequent auditory dysfunction
