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doi: 10.3389/fphar.2025.1632588 Received 21 May 2025 Accepted 28 July 2025 Published 29 August 2025 Volume 16 - 2025 Edited by Yurong Lai, Gilead, United States Reviewed by Daniel Crona, University of North Carolina at Chapel Hill, United States John Prybylski, Pfizer, United States Updates Copyright 2025 Cao, Qian, Wang, Zheng, Huang, Wei, Jiang, Yu, Jiang, Yu, Mao and Zhai

Distinct protocols of ethanol administration result in different effects on brain phospholipid composition, ranging from a reduction in some saturated FA (12:0, 14:0, and 16:0) and a rise in 18:0 without diet effects (38), to unaffected levels of saturated FA (39)

The treatment lasted 6 months, and the results obtained showed that in the subjects treated with ALA, the mean level of total GSH in the blood and CD4+ T-cell proliferation were significantly elevated compared to the subjects taking the placebo

Pair-fed control (CON) mice received a LD diet in which the EtOH content was substituted by carbohydrates

Each generation of incretin therapy produces greater weight loss than the last

In contrast, dopamine and serotonin levels were reduced compared to the healthy population, which could underline the diffuse pain sensation and discomfort [16]