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4D-printed matrices enable shape-memory and stimuli-responsive degradation, while biosensor-integrated dressings unite therapeutic release with continuous monitoring of ROS, pH, and temperature

The 2023 Phase II scar study (Hosokawa et al., n=40 post-surgical patients) found 0.5% GHK-Cu gel reduced scar volume by 35% at 3 months with 2.5-fold fibroblast proliferation versus silicone controls

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