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Depression and inflammation: an intricate relationship

Each group contained 10 rats

Protrusion of pseudopodia (increased volume in cell projections) and shrinkage of their retracted rear cell bodies occur with oscillations of cell membrane potential and osmotic changes via KCl uptake and release through potassium and chloride channels, with aquaporin participation and possibly K + refilling/recycling [37,38,39,40,41,42]

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These changes in turn are accompanied by increased ROS production in sensory neurons and spinal cord, although the mechanisms leading to altered mitochondrial function are relatively poorly understood (Doyle et al., 2012

Boukhenouna, S