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This dual activation mechanism provides redundancy ensuring robust nitric oxide production for vasodilation and vascular protection

These studies suggest that in addition to its role in physiologic copper absorption, ATP7A fills a host defense function by transporting antibacterial quantities of copper ions to phagolysosomal compartments containing engulfed bacteria

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Both ER66 and ER36 are expressed in -cells (299)

[DOI] [PMC free article] [PubMed] [Google Scholar] [62].Andreou A, Trantza S, Filippou D, Sipsas N, Tsiodras S

[DOI] [PubMed] [Google Scholar] 133.Hessl D., Libero L., Schneider A., Kerns C., Winder-Patel B., Heath B., Lee J., Coleman C., Sharma N., Solomon M., et al