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Topiramate affords neuroprotection in diabetic neuropathy model via downregulating spinal GFAP/inflammatory burden and improving neurofilament production

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It has the potential to alleviate symptoms of depression, as well as reduce anxiety and stress, by modulating brain signaling

Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-B-dependent manner