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This allows researchers to test a range of doses on a smaller cohort, identifying the minimum effective dose and any potential adverse effects before committing to a larger, more resource-intensive study

This designation allows use strictly for in vitro testing and laboratory experimentation

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The mechanism of action for AOD 9604 involves stimulating fat breakdown and fat oxidation in adipose tissue, supporting research into its potential as a treatment for obesity and metabolic disorders

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NNMT is upregulated in the white adipose tissue of obese animals and humans, and its activity is mechanistically linked to depleted cellular NAD+ and SAM pools