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PD-MCI patients compared to PD-NC showed a more widespread degeneration of dopaminergic terminals in the caudate nucleus (Sasikumar and Strafella, 2020), while degeneration of the medial substantia nigra caused dysfunction of striato-frontal and mesocortico-limbic loss (Martnez-Horta and Kulisevsky, 2011)

Tetramer-visualized gluten-specific CD4 + T cells in blood as a potential diagnostic marker for coeliac disease without oral gluten challenge

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This figure is based on an extrapolation of figures from the United Kingdom 2

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So free radicals, heavy metals, and environmental toxins stick to it