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doi: 10.1021/jf2002188 124

Tusamitamab ravtansine, a CEACAM5-directed ADC, exemplifies structural modularity: a humanized monoclonal antibody targeting CEACAM5s extracellular domain is site-specifically conjugated via a reducible disulfide linker to the maytansinoid DM4 (70), a microtubule-disrupting payload engineered for bystander effect potentiation

Because the duration of the effect of flumazenil is shorter than the effect of the benzodiazepine, recurrence of symptoms should be expected

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Kaczmarek, J