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Conclusion and recommendations Curcumin demonstrates considerable promise as an adjunct in gynecologic care due to its anti-inflammatory, antioxidant, and antineoplastic properties

[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Konosic S., Petricevic M., Ivancan V., Konosic L., Goluza E., Krtalic B., Drmic D., Stupnisek M., Seiwerth S., Sikiric P

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Activated CAFs facilitate tumor cell growth, invasiveness, and drug resistance by depositing extracellular matrix (ECM) and secreting cytokines, chemokines, and growth factors (zdemir et al., 2014)

Interestingly, combination therapy reshaped the tumor microenvironment via cytokines associated with natural killer cells, supported by eradication of immune checkpoint galectin-1 and elevated granzyme B levels

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