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Ferroptosis can be induced by genetically deleting GPX4 or by using small molecules that either covalently inhibit GPX4 (e.g., RSL3) or promote its degradation (e.g., FIN56) [33, 39, 40]

doi: 10.1371/journal.pone.0186802 184 DomingoJCCordobillaBFerrerRGiraltMAlegre-MartnJCastro-MarreroJ

J Exp Med 208:13391350

[DOI] [PubMed] [Google Scholar] 32.Iyer LM, Abhiman S, Maxwell Burroughs A, Aravind L

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ADMETlab 2.0 (Su et al., 2007): A website for predicting the physicochemical properties of compounds, the ADME properties, and the toxicity correlations