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Classic signaling tends to promote immune homeostasis, while trans-signaling has been implicated in inflammatory processes and is associated with metabolic disorders [28]

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Therefore, it is suggested that the mutation of Asp240 (into Thr240 and Lys240) leads to the disturbance of the above described hydrogen-network, which ultimately affects the enzymes activity

Role of glutathione in winemaking: a review

Lipoxygenases (LOXs), non-heme iron-containing enzymes, catalyze the stereospecific oxygenation of free polyunsaturated fatty acids (PUFAs) into lipid hydroperoxides through molecular oxygen incorporation