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Unlike programmed cell death pathways such as apoptosis and necroptosis, necrosis is typically triggered by acute insults (e.g., energy depletion, ionic imbalance, or physicochemical damage) without sophisticated molecular regulation [172] (Fig

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Other sources of superoxide include enzymatic reactions that transfer electrons to the electron transport chain (eg, mitochondrial glycerol 3-phosphate dehydrogenase (mGPDH), and the last step of -oxidation, electron-transferring flavoprotein ubiquinone oxidoreductase (ETFQOR), pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH), and branched-chain 2-oxoacid dehydrogenase (BCKDH))

CYP2C9 Activity in SD Rats after 30-Day Treatment CYP2C9 enzyme activity was higher in the phenobarbital- and Cellgevity-treated groups in comparison with the N-C group