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10.1142/s0192415x22500434 213 WangL

keap1, kelch-like ECH-associated protein 1

The conjugation of prodrugs with antibodies, nanobodies, aptamers, syderomycins, polymers, cell-penetrating peptides, lipids, polyethyleneglycol (PEG), and carbohydrates has greatly expanded the potential applications of this technology, fostering meaningful advancements in the use of this optimization approach [8,9,10,11,12]

7.4 Alkaloids: suppressors of apoptosis and metabolic dysfunction Alkaloids attenuate ALD by suppressing the MAPK/NF-B axis, thereby reducing ERK/JNK phosphorylation and TNF- production, which mitigates hepatocyte apoptosis ( Oxymatrine, a quinolizidine alkaloid from the roots of Sophora flavescens Aiton [Fabaceae], inhibits ERK1/2-mediated apoptosis and downregulates pro-inflammatory cytokines ( Berberine, an isoquinoline alkaloid from traditional Chinese medicinal herbs such as Coptis chinensis Franch

Ingredients Aqua (Water), Paraffinum Liquidum (Mineral Oil), Glyceryl Stearate SE, Glycerin, Stearic Acid, Palmitic Acid, Parfum (Fragrance), Glutathione, Ascorbyl Tetraisopalmitate, Diacetyl Boldine, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Disodium EDTA, Carbomer, Triethanolamine, Phenoxyethanol, Methylparaben, Ethylparaben, Propylparaben, Imidazolidinyl Urea, Alpha-Isomethyl Ionone, Benzyl Alcohol The lists of ingredients used in the composition of the FAIR & WHITE brand products are regularly updated

Arthralgia was present in 14.3% of patients