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Prevention of metabolic syndrome is achieved through changes in heart-healthy lifestyle, such as a healthy diet, weight loss, stress management, regular physical activity, and smoking cessation [99]

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doi: 10.1055/s-2007-978596

The histologic microstaging system of Clark, used in cutaneous melanoma, cannot be applied to oral mucosa, because of the lack of histologic landmarks analogous to papillary and reticular dermis (34)
