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There was no significant differences between the effects of the daily oral maintenance dosages of 2 g and 6 g on heart failure (RR=0.53, 95% CI [0.25-1.13], P=0.10), unstable angina (RR=0.90, 95% CI [0.51-1.58], P=0.71), or myocardial reinfarction (RR=0.74, 95% CI [0.30-1.80], P=0.50)

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It is becoming increasingly clear that mitochondria drive cellular functions and in vivo phenotypes by directing the production rate and abundance of metabolites that are proposed to function as signaling molecules (Chandel 2015
