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This finding suggests that the site of ROS generationwhether in the mitochondrial electron transport chain or through cytosolic enzymesmay play a role in the maintenance of AML LSCs

Given the critical role of GPX4 in ferroptosis, further investigation into GPX4-mediated T cell ferroptosis and its regulation would be of great significance for understanding and potentially treating LN

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Exposure of bronchial epithelial cells to cigarette smoke decreased HDAC3 and HDAC2 activity/expression and nuclear translocation of the glucocorticoid receptor (GR), contributing to steroid resistance [45,46]

304 Furthermore, endothelial progenitor cells from diabetic patients show a reduced reendothelialization capacity that can be normalized through inhibition of p47 phox

doi: 10.1016/j.scienta.2017.12.032 39 ChenQ.WuK.-H.WangP.YiJ.LiK.-Z.YuY.-X.et al