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[21] [22] Clinical significance [edit] Patients with mutations in the GSS gene develop glutathione synthetase (GSS) deficiency, an autosomal recessive disorder

* Correspondence: Fan Guo, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Benabid and colleagues' studies, which activated the ventral intermediate nucleus of the thalamus, marked the beginning of the contemporary age of chronic deep brain stimulation (DBS), even though stimulation of the deep parts of the brain had been done before

In earlier clinical trials, IGV-001 demonstrated good tolerance and safety (NCT02507583)

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