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GSH-targeted Nanosponges Increase Doxorubicin-Induced Toxicity " In Vitro " and " In Vivo " in Cancer Cells with High Antioxidant Defenses

elegans lacking the ads-1 gene, encoding AGPS, or human HT-1080 cells treated with an AGPS inhibitor showed increased lipid peroxidation and ferroptosis rates 139

This study was a single-arm pilot trial where 24 patients completed a 12-week low-residue fiber diet

Yin et al., 2014

This is the first time, to the best of our knowledge, that enteral NAC has been used to establish a dose that provides adequate plasma concentrations and a desired CNS GSH pharmacodynamic response in infants