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Such direct effect can ascertain channel functioning in disturbed electrolyte circumstances (i.e., hyperkalemic [83] and hypokalemic [84] or hypermagnesemic [85] condition) and counteraction of channel disturbances that were induced using the agents that otherwise block channel function

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Funding This study was supported by the Canadian Institutes of Health Research (grant number MOP-64345) and in part by the Ontario Ministry of Health and Long Term Care

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