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We then summarize progress in elucidating the molecular mechanisms underlying the role of the ECM during normal morphogenesis, focusing on the best known examples: the development of the intestine, the lungs and the mammary and submandibular glands (also known as salivary glands)

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Furthermore, the role of luminal microbes in SLE development is reinforced by the fact that patients express the LTA receptor, TLR2, in greater abundance when compared to healthy controls, and the removal of commensal microbes via antibiotic treatment can ameliorate disease symptoms (Liu et al

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