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in Cellular and Molecular Biology through a joint program between the Open University of London, UK and the San Raffaele Scientific Institute, Milan, Italy

To overcome cysteines instability and toxicity, its acetylated form, N-acetylcysteine (NAC), has been approved by the Food and Drug Administration (FDA) for treatment of acetaminophen-induced hepatotoxicity during pregnancy , 14,15,16,17,18 and chorioamnionitis

doi: 10.1111/j.1471-4159.2006.03907.x

Das zentrale Organ fr die Biotransformation ist die Leber, unser zentrales Entgiftungsorgan

The underlying mechanism why the compound exhibited the selective cytotoxicity toward tumor cells over non-tumor cells are not fully understood, but it might have reflected the alterations of GST activities in the cells 30 , and the detailed study along this line is currently ongoing

This mechanism is particularly vital for patients with chronic illnesses, whose cellular transport mechanisms may be impaired by chronic inflammation or mitochondrial dysfunction