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Mice carrying null mutations of the genes encoding insulin-like growth factor I ( Igf-1 ) and type 1 IGF receptor ( Igf1r )

10.1016/j.canlet.2009.09.002 Cancer Lett
Peptides used therapeutically are designed to bind to specific cell receptors in order to trigger the specific responses that have slowed down, like collagen production
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They play a crucial role in various biological processes, including healing, hormone regulation, and metabolism
