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Lipoyl (octanoyl) transferase 2 catalyzes the transfer of the octanoyl moiety from ACP to a conserved lysine in the H protein of the glycine cleavage complex (see Biological Activities and Figure 3)

The first step is mediated by -glutamylcysteine synthetase (GCLC), which catalyzes the -amide bond between the -carboxyl group of glutamate and the amino group of cysteine to form -glutamyl-cysteine (-Glu-Cys)

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405,432 Incidentally, acupuncture at the Zusanli (ST36) acupoint that is used to treat depressive symptoms, prevented the development of both astrocytic atrophy and depressive-like behaviours in mice subjected to chronic stress regimen

Methionine also functions to protect our neurological system