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ALC is unique because of its ability to cross the blood brain barrier, the protective layer of cells that filter nutrients and molecules access to the brain

Contributions of depressive mood and circulating inflammatory markers to coronary heart disease in healthy European men: The Prospective Epidemiological Study of Myocardial Infarction (PRIME) Circulation

For instance, a 2017 review showed that taking L-carnitine for 3 days had no effect on markers of brain function including reaction time, vigilance, immediate memory, and delayed recall in young adults without cognitive impairment

Notably, the enantiomer D-carnitine may exert hepatotoxic effects (89), underscoring the critical importance of compound-specific safety evaluation and reinforcing that only the biologically active L-isomer should be considered for therapeutic use in MASLD

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doi: 10.1053/j.jrn.2020.04.007