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doi: 10.1007/s00109-021-02065-3 428 MastrapasquaMRossiRDe CosmoLRestaAErredeMBizzocaAet al

J Biol Chem (2019) 294:662134

Metabolites 10 , 49 (2020)

The pathogenesis of cataracts is closely linked to oxidative stress, which damages lens proteins and lipids, primarily in the epithelial layer [9, 10]

Acetyl L-Carnitine (ALC) is a highly bioavailable form of L-carnitine that crosses the blood-brain barrier to support cognitive function, neurological health, mood balance, and energy production.* ALC promotes mitochondrial function, neurotransmitter synthesis, and antioxidant activity, making it a valuable tool for supporting brain health, nerve comfort, and overall metabolic vitality.* The acetyl derivative of L-carnitine, acetyl-L-carnitine is involved in the metabolism of protein, carbohydrates and fats, as well as the conversion of fats into energy.* Carnitine shuttles fats (triglycerides) into the mitochondria so these fats can be used for fuel.* Acetyl-L-carnitine crosses the blood brain barrier more readily than L-carnitine

Similarly, the results of screening and comparing all participants in the male control and male MDD groups (Figures 5DF) and comparing all participants in the female control and female MDD groups (Figures 5GI), compared to the control group, the MDD exhibited a lower concentration of acetylcarnitine and this was a statistically significant difference regardless of exposure to drug treatment