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The primary treatment approach for patients with MIS-C involves the use of immunomodulatory medications, including intravenous immunoglobulin (IVIG), which is a blood product containing antibodies from numerous healthy donors, as well as corticosteroids [2, 27, 28]

It is likely that this imposed stress is pertinent to dry eye induced ocular pain even though in these patients the hyperosmotic threshold for inducing pain through TRPV1 activation is unclear [29]

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The selection of this type of mice was based on the previous studies on mice with EIF (Jinchun and Jie, 2011