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They are tetramers, where each monomer consists of six transmembrane domains (TM) (S1-S6) (Bae et al., 2018

Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA, Somasundaran M, Sullivan JL, Luzuriaga K, Greenough TC, Choe H, Farzan M (2003) Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

doi: 10.1001/archneurol.2011.233

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Prospective randomized controlled studies of oral vitamin B12 treatment in patients with vitamin B12 deficiency, including patients with Biermers disease [21,22] In a first study, Kuzminski et al