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In mice, KOR activation reduces synaptic transmission from the lateral amygdala to the BLA and blocks LTP induction in the BLA (Huge et al., 2009)

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Significant increase in the abundance of serine proteases is consistent with the upregulation of proteolytic enzymes reported by 3.5 Peroxisomal proteins involved in -oxidation and detoxification of reactive species are upregulated Peroxisomes are important organelles involved in lipid homeostasis, ROS detoxification, and secondary metabolite metabolism (Steinberg, 2016)

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