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An early study demonstrated a protective effect of UA on spontaneous death of dopaminergic neurons in culture, with an antioxidant mechanism targeting Fe-produced reactive oxygen species 37

Within the dentate gyrus, a decrease in spiking frequency was observed following exposure to JP-5 and FT, although the decrease did not reach significance in the FT exposure group

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Consistently, our untargeted NMR enrichment analysis showed biochemical alterations in all these energy-related metabolic pathways (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Wang H, He X, Zhang L, et al