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J Nutr 2012;142:112-6

Astaxanthin is originally lipid-soluble=hydrophobic but has hydrophilic ends at both sides of its structure, so it spans across the membrane and quenches ROS on both surface and inside of the cells

113 , 114 , 116 Of note, how this advantage of modulating NO-system (i.e., particular effect on eNOS gene), may be a practical background which could be further translated into an enhanced clinical performance

Patients with this condition cannot absorb B12 from food or oral supplements and require lifelong intramuscular replacement therapy

More importantly, these results were not replicated in further studies

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